STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
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[Homology]
Score
Arch_1293KEGG: bfa:Bfae_24070 hypothetical protein; SPTR: D0WNU3 Putative membrane protein; PFAM: Protein of unknown function (DUF3017). (90 aa)    
Predicted Functional Partners:
Arch_1294
Hypothetical protein; KEGG: xce:Xcel_0736 PE-PGRS family protein; SPTR: D0WNV5 Putative uncharacterized protein.
       0.781
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.605
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.601
Arch_1292
LPXTG-motif cell wall anchor domain protein; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR000421:IPR006104:IPR006102:IPR006103:IPR 011081:IPR011080:IPR013781:IPR019931:IPR017853:IPR008979:I PR006101; KEGG: apv:Apar_0102 glycoside hydrolase family 2 sugar binding; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; Ig domain protein; coagulation factor 5/8 type domain protein; SPTR: A4K5H9 Beta-galactosidase BbgIII; TIGRFAM: LPXTG-motif cell wall anchor dom [...]
       0.443
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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