STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1294Hypothetical protein; KEGG: xce:Xcel_0736 PE-PGRS family protein; SPTR: D0WNV5 Putative uncharacterized protein. (387 aa)    
Predicted Functional Partners:
Arch_1293
KEGG: bfa:Bfae_24070 hypothetical protein; SPTR: D0WNU3 Putative membrane protein; PFAM: Protein of unknown function (DUF3017).
       0.782
Arch_1641
DSBA oxidoreductase; InterPro IPR012336:IPR001853:IPR012335; KEGG: xce:Xcel_2947 DsbA oxidoreductase; PFAM: DSBA oxidoreductase; SPTR: D0WJV3 Putative uncharacterized protein; PFAM: DSBA-like thioredoxin domain.
  
     0.710
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.690
Arch_0865
Hypothetical protein; KEGG: tcu:Tcur_2317 transcriptional regulator-like protein; SPTR: D0WMW9 Putative uncharacterized protein.
  
     0.689
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.687
Arch_0224
Domain of unknown function DUF1794; May play a role in the intracellular transport of hydrophobic ligands; Belongs to the UPF0678 family.
  
     0.680
Arch_1068
InterPro IPR011251; KEGG: bcv:Bcav_1628 hypothetical protein; SPTR: D0WNB4 Nitrilotriacetate monooxygenase.
  
     0.678
Arch_1422
KEGG: bcv:Bcav_1208 hypothetical protein; SPTR: D0WPI0 Putative uncharacterized protein.
  
    0.676
Arch_0374
KEGG: bcv:Bcav_1331 hypothetical protein; SPTR: D0WRU5 Putative uncharacterized protein (Fragment).
  
     0.660
Arch_1231
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: jde:Jden_0711 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: D0WNM4 Helicase, UvrD/Rep family; PFAM: Domain of unknown function DUF83; UvrD/REP helicase.
  
     0.658
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.