STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1297COGs: COG1835 acyltransferase; InterPro IPR002656:IPR013830; KEGG: kse:Ksed_15740 predicted acyltransferase; PFAM: acyltransferase 3; SPTR: C7NI82 Predicted acyltransferase; PFAM: Acyltransferase family. (667 aa)    
Predicted Functional Partners:
Arch_1298
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_3026 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: Q1M2Q1 Helicase; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA.
       0.791
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.497
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.492
Arch_1299
LPXTG-motif cell wall anchor domain protein; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR002860:IPR019931:IPR011040; KEGG: bln:Blon_2348 exo-alpha-sialidase; PFAM: glycosyl hydrolase BNR repeat-containing protein; SPTR: B7GNQ0 Exo-alpha-sialidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: BNR/Asp-box repeat.
       0.452
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.