STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (390 aa)    
Predicted Functional Partners:
Arch_1315
Phosphate acetyltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR004614; KEGG: bfa:Bfae_08770 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; SPTR: D0WNY9 Putative phosphate acetyltransferase pta; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
 
 
 0.999
Arch_1317
GCN5-related N-acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sgr:SGR_127 putative acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A7B9Y5 Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family.
     
 0.784
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
     
 0.778
Arch_0899
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.673
Arch_0346
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR001078:IPR001017:IPR005475:IPR011603; KEGG: bcv:Bcav_1274 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; SPTR: D0WRR3 Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2- [...]
  
  
 0.647
Arch_0022
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: nml:Namu_5228 protein of unknown function DUF162; PFAM: protein of unknown function DUF162; SPTR: A7BE65 Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
  
  
 0.522
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
     
 0.512
Arch_0043
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR013785; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Q6AAL0 Transaldolase; PFAM: Transaldolase.
     
 0.494
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
     
 0.477
Arch_1670
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR013027:IPR004099; KEGG: cdi:DIP1748 putative oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: C2CQM4 CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
  
 0.474
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.