STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Arch_1323Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)    
Predicted Functional Partners:
Arch_1554
Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
  
 0.996
Arch_1322
COGs: COG3634 Alkyl hydroperoxide reductase large subunit; InterProIPR012081:IPR002109:IPR013027:IPR012335:IPR 012336:IPR000103:IPR008255; KEGG: nar:Saro_1718 pyridine nucleotide-disulphide oxidoreductase, class-II, active site; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Q3KC40 Alkyl hydroperoxide reductase subunit; TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: alkyl hydroperoxide reductase, F subunit.
 
  
 0.994
Arch_1810
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.944
Arch_0748
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.885
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.788
Arch_0688
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bcv:Bcav_1772 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: C5C4Q0 Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
  
 0.701
Arch_0393
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase.
    
 
 0.662
Arch_1067
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.657
Arch_1466
COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR002177:IPR008331:IPR012347:IPR009078; KEGG: pac:PPA2134 starvation-inducible DNA-binding protein or fine tangled pili major subunit; PFAM: Ferritin Dps family protein; SPTR: A7BBG2 Putative uncharacterized protein; PFAM: Ferritin-like domain; Belongs to the Dps family.
  
  
 0.640
Arch_0376
COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: D0WRU8 Thioredoxin-related protein; PFAM: Thioredoxin.
  
 
 0.626
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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