STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-2Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (98 aa)    
Predicted Functional Partners:
Arch_0575
Protein of unknown function DUF2469; InterPro IPR019592; KEGG: jde:Jden_0992 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: D0WR58 Putative CTP synthase; PFAM: Protein of unknown function (DUF2469).
  
     0.719
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.670
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
   
 0.660
Arch_0869
InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2099 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: C5C6E6 Transcriptional regulator, MerR family.
  
     0.590
Arch_1325
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
       0.588
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
 
   
0.588
Arch_0881
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
     0.535
Arch_1514
Protein of unknown function DUF501; COGs: COG1507 conserved hypothetical protein; InterPro IPR007511; KEGG: jde:Jden_1921 protein of unknown function DUF501; PFAM: protein of unknown function DUF501; SPTR: D0WQ08 Septum formation initiator family protein; PFAM: Protein of unknown function (DUF501).
  
     0.525
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.514
Arch_0907
Conserved hypothetical protein; COGs: COG2887 RecB family exonuclease; KEGG: sco:SCO1653 hypothetical protein; SPTR: D0WMN9 RecB family exonuclease; PFAM: Protein of unknown function (DUF2800).
  
     0.494
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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