STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Arch_1361COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR017871; KEGG: ele:Elen_1832 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WP04 CoA ligase; PFAM: AMP-binding enzyme. (500 aa)    
Predicted Functional Partners:
Arch_1363
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR013786:IPR 013764:IPR009100:IPR009075; KEGG: drm:Dred_0570 crotonobetainyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: D0WP06 Crotonobetainyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
  
 0.887
Arch_1362
L-carnitine dehydratase/bile acid-inducible protein F; COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: ele:Elen_1833 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: D0WP05 Crotonobetainyl-CoA:carnitine CoA-transferase; PFAM: CoA-transferase family III.
 
  
 0.886
Arch_1360
InterPro IPR002539; KEGG: drm:Dred_0577 dehydratase; PFAM: MaoC domain protein dehydratase; PRIAM:3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-ch olest-24-enoyl-CoAhydratase; SPTR: D0WP03 Putative MaoC like domain protein; PFAM: MaoC like domain.
 
  
 0.860
Arch_1364
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094:IPR002168; KEGG: ele:Elen_1835 alpha/beta hydrolase fold-3 domain protein; PFAM: Alpha/beta hydrolase fold-3 domain protein; SPTR: D0WP07 Acetyl esterase; PFAM: alpha/beta hydrolase fold.
 
 
 0.813
Arch_1365
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701:IPR016196; KEGG: ele:Elen_1836 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: D0WP08 Transporter, major facilitator family; PFAM: Major Facilitator Superfamily.
 
    0.765
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
  0.664
Arch_1359
General substrate transporter; COGs: COG2814 Arabinose efflux permease; InterPro IPR005828:IPR016196:IPR002345:IPR005829; KEGG: drm:Dred_0578 general substrate transporter; PFAM: General substrate transporter; SPTR: A4J217 General substrate transporter; PFAM: Sugar (and other) transporter.
 
    0.616
Arch_0284
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: bcv:Bcav_3247 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WMF4 O-succinylbenzoate--CoA ligase; PFAM: AMP-binding enzyme.
  
     0.609
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
   0.587
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.585
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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