STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Arch_1364Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094:IPR002168; KEGG: ele:Elen_1835 alpha/beta hydrolase fold-3 domain protein; PFAM: Alpha/beta hydrolase fold-3 domain protein; SPTR: D0WP07 Acetyl esterase; PFAM: alpha/beta hydrolase fold. (320 aa)    
Predicted Functional Partners:
Arch_1362
L-carnitine dehydratase/bile acid-inducible protein F; COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: ele:Elen_1833 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: D0WP05 Crotonobetainyl-CoA:carnitine CoA-transferase; PFAM: CoA-transferase family III.
 
  
 0.910
Arch_1365
Major facilitator superfamily MFS_1; COGs: COG2271 Sugar phosphate permease; InterPro IPR011701:IPR016196; KEGG: ele:Elen_1836 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: D0WP08 Transporter, major facilitator family; PFAM: Major Facilitator Superfamily.
 
     0.904
Arch_1360
InterPro IPR002539; KEGG: drm:Dred_0577 dehydratase; PFAM: MaoC domain protein dehydratase; PRIAM:3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-ch olest-24-enoyl-CoAhydratase; SPTR: D0WP03 Putative MaoC like domain protein; PFAM: MaoC like domain.
 
  
 0.854
Arch_1361
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR017871; KEGG: ele:Elen_1832 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WP04 CoA ligase; PFAM: AMP-binding enzyme.
 
 
 0.840
Arch_1363
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR013786:IPR 013764:IPR009100:IPR009075; KEGG: drm:Dred_0570 crotonobetainyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: D0WP06 Crotonobetainyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
  
 0.836
Arch_1359
General substrate transporter; COGs: COG2814 Arabinose efflux permease; InterPro IPR005828:IPR016196:IPR002345:IPR005829; KEGG: drm:Dred_0578 general substrate transporter; PFAM: General substrate transporter; SPTR: A4J217 General substrate transporter; PFAM: Sugar (and other) transporter.
 
     0.709
Arch_0299
NADH-quinone oxidoreductase, chain G; COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterProIPR001041:IPR019574:IPR006656:IPR010228:IPR 000283; KEGG: xce:Xcel_0475 NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molybdopterin oxidoreductase; SPTR: D0WMG7 NADH dehydrogenase, G subunit; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; TIG [...]
   
 
 0.607
Arch_0298
NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
    
   0.594
Arch_0297
COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023:IPR005113:IPR012336; KEGG: xce:Xcel_0473 NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: D0WMG5 NADH dehydrogenase I, E subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit.
    
   0.585
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.492
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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