STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1414FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR000759; KEGG: bcv:Bcav_3195 ferredoxin--NADP(+) reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WPH0 Ferredoxin--NADP reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (460 aa)    
Predicted Functional Partners:
Arch_1023
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017938:IPR012165:IPR017927:IPR008333:IPR 001433:IPR019480:IPR001834; KEGG: oih:OB1492 dihydroorotate dehydrogenase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: B0MVE6 Putative uncharacterized protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorota [...]
  
 
 0.938
Arch_0935
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase; InterPro IPR017941; KEGG: bcv:Bcav_2338 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: C1RHU4 Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase; PFAM: Rieske [2Fe-2S] domain.
     
 0.912
Arch_0585
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014729:IPR014730:IPR012255; KEGG: pac:PPA2214 putative electron transfer flavoprotein (FixA protein); PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: D0WNZ9 Putative electron transfer flavoprotein; PFAM: Electron transfer flavoprotein domain.
  
 
 0.653
Arch_1356
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR012255:IPR014730:IPR014729; KEGG: pac:PPA2214 putative electron transfer flavoprotein (FixA protein); PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: D0WNZ9 Putative electron transfer flavoprotein; PFAM: Electron transfer flavoprotein domain.
  
 
 0.653
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.622
Arch_0202
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterProIPR006097:IPR006096:IPR016040:IPR014362:IPR 006095; KEGG: jde:Jden_2359 glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: C0W243 Glutamate dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.598
Arch_0774
InterPro IPR016566; KEGG: xce:Xcel_1919 hypothetical protein; SPTR: D0WQI0 Putative integral membrane protein; PFAM: Protein of unknown function (DUF3159).
 
     0.572
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
  
 0.571
Arch_0604
DivIVA domain repeat protein; InterPro IPR019932:IPR019933; KEGG: bcv:Bcav_2501 hypothetical protein; SPTR: D0WR37 DivIVA domain repeat protein; TIGRFAM: DivIVA domain repeat protein; DivIVA domain; TIGRFAM: DivIVA domain; DivIVA domain repeat protein.
  
     0.545
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
 
     0.538
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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