STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1416COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: bcv:Bcav_1243 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: D0WPH2 Competence protein F; PFAM: Phosphoribosyl transferase domain. (233 aa)    
Predicted Functional Partners:
Arch_1417
Lipoprotein LpqB, GerMN domain protein; InterPro IPR019606:IPR018910; KEGG: bcv:Bcav_1242 lipoprotein LpqB; PFAM: Lipoprotein LpqB, GerMN domain; Lipoprotein LpqB, beta-propeller domain-like; SPTR: D0WPH3 Putative lipoprotein LpqB; PFAM: Lipoprotein LpqB beta-propeller domain; Sporulation and spore germination.
 
     0.873
Arch_1418
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1241 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: D0WPH4 Sensor histidine kinase MtrB; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
    0.842
Arch_1419
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: mva:Mvan_1752 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0WPH5 DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
    0.812
Arch_0578
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: bcv:Bcav_2511 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: D0WR54 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
 
 0.778
xerC
Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
   
    0.756
apt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.723
Arch_1420
KEGG: bcv:Bcav_1215 hypothetical protein; SPTR: D0WPH8 Putative uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF3499).
       0.709
Arch_1421
KEGG: xce:Xcel_2545 hypothetical protein; SPTR: D0WPH9 Putative uncharacterized protein; manually curated.
 
     0.692
Arch_0333
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
  
    0.689
Arch_0068
ABC transporter related protein; COGs: COG1134 ABC-type polysaccharide/polyol phosphate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: lxx:Lxx05010 lipopolysaccharide exporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C1RIM8 ABC-type polysaccharide/polyol phosphate transport system, ATPase component; PFAM: ABC transporter.
   
    0.671
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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