STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Arch_1432Maf protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (211 aa)    
Predicted Functional Partners:
Arch_1431
Protein of unknown function DUF885; COGs: COG4805 conserved hypothetical protein; InterPro IPR010281; KEGG: bcv:Bcav_1144 protein of unknown function DUF885; PFAM: protein of unknown function DUF885; SPTR: D0WPL9 Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF885).
       0.822
Arch_0694
TIM-barrel protein, nifR3 family; COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR018517:IPR013785:IPR004652:IPR001269; KEGG: xce:Xcel_2165 TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; SPTR: D0WQT3 Putative tRNA-dihydrouridine synthase; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family.
 
     0.762
Arch_1430
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR009061; KEGG: bcv:Bcav_1154 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; PRIAM: Adenylate cyclase; SPTR: D0WPL7 Putative adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
       0.636
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
   
  
 0.528
Arch_1428
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1156 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WPL5 Putative two-component system histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
  
 0.512
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
      
 0.495
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.487
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
  
  
 0.461
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.434
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.428
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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