STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1452KEGG: krh:KRH_07740 hypothetical protein; SPTR: C6RBJ7 Putative uncharacterized protein. (181 aa)    
Predicted Functional Partners:
Arch_0305
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR001750:IPR010227:IPR003918; KEGG: bcv:Bcav_3217 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: D0WMH3 NADH-quinone oxidoreductase, M subunit; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
    
 
 0.678
Arch_0096
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
  0.602
Arch_1036
Sulphate transporter; COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR002645:IPR006162:IPR011547; KEGG: gbr:Gbro_3908 sulphate transporter; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: D0L3T1 Sulphate transporter; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: high affinity sulphate transporter 1.
    
   0.602
Arch_1451
Isocitrate dehydrogenase, NADP-dependent; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: sma:SAV_7214 isocitrate dehydrogenase; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: Q826H9 Putative isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family.
       0.577
nuoH
Respiratory-chain NADH dehydrogenase subunit 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
    
   0.556
nuoA
NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.
    
   0.537
Arch_0139
KEGG: bcv:Bcav_2625 hypothetical protein; SPTR: D0WKD8 Putative uncharacterized protein.
  
  0.510
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.476
Arch_1252
InterPro IPR017896:IPR017900:IPR001450; KEGG: cur:cur_0829 hypothetical protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C2BU46 Putative uncharacterized protein.
   
   0.476
nuoC
NADH (or F420H2) dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
   
   0.454
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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