STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1455Alpha/beta hydrolase fold protein; InterPro IPR000073:IPR002410; KEGG: cef:CE0596 putative prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold; SPTR: Q8FS10 Putative prolyl aminopeptidase; PFAM: alpha/beta hydrolase fold. (418 aa)    
Predicted Functional Partners:
Arch_1454
COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529:IPR011234; KEGG: bja:blr1240 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: Q89V18 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
  
  
 0.787
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
      0.766
Arch_1456
KEGG: krh:KRH_21190 hypothetical protein; SPTR: C2BVW5 Putative uncharacterized protein.
  
    0.605
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.555
Arch_1363
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR013786:IPR 013764:IPR009100:IPR009075; KEGG: drm:Dred_0570 crotonobetainyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: D0WP06 Crotonobetainyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
   
 
 0.479
Arch_1670
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR013027:IPR004099; KEGG: cdi:DIP1748 putative oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: C2CQM4 CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
 
 0.438
Arch_0403
InterPro IPR011991:IPR005149; KEGG: art:Arth_0527 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: C2KN54 PadR family transcriptional regulator; PFAM: Transcriptional regulator PadR-like family.
 
     0.430
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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