STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
Arch_1458PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...] (659 aa)    
Predicted Functional Partners:
Arch_0158
Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883:IPR013781:IPR017853:IPR001540; KEGG: sco:SCO4860 secreted hydrolase; PFAM: Glycoside hydrolase, family 20, catalytic core; SPTR: C8P1S6 Lacto-N-biosidase; PFAM: Glycosyl hydrolase family 20, catalytic domain.
  
  
 0.999
Arch_0722
Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
  
 0.999
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
 
 0.999
Arch_1460
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.995
Arch_1459
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR004341; KEGG: bad:BAD_0367 transcription antiterminator LicT; PFAM: CAT RNA-binding domain protein; PRD domain protein; SPTR: B1S6B5 Putative uncharacterized protein; PFAM: CAT RNA binding domain; PRD domain.
 
 0.993
Arch_1461
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032:IPR005698:IPR001020; KEGG: cef:CE1830 putative PTS phosphohistidine-containing protein; PFAM: phosphoryl transfer system HPr; SPTR: A7BEU7 Putative uncharacterized protein; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
  
 0.988
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
  
 
 0.975
Arch_1590
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR004341; KEGG: dda:Dd703_1406 transcriptional antiterminator, BglG; PFAM: PRD domain protein; CAT RNA-binding domain protein; SPTR: C2GFH3 Transcriptional antiterminator; PFAM: CAT RNA binding domain; PRD domain.
 
 
 0.968
Arch_1588
PTS system, glucose subfamily, IIA subunit; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127:IPR011055; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component.
 
 
0.963
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.958
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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