STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1466COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR002177:IPR008331:IPR012347:IPR009078; KEGG: pac:PPA2134 starvation-inducible DNA-binding protein or fine tangled pili major subunit; PFAM: Ferritin Dps family protein; SPTR: A7BBG2 Putative uncharacterized protein; PFAM: Ferritin-like domain; Belongs to the Dps family. (153 aa)    
Predicted Functional Partners:
Arch_1115
ATP-dependent Clp protease adaptor protein ClpS; COGs: COG2127 conserved hypothetical protein; InterPro IPR014719:IPR003769; KEGG: sco:SCO2916 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: C4DNG9 Uncharacterized conserved protein, COG2127; PFAM: ATP-dependent Clp protease adaptor protein ClpS.
   
 
 0.893
Arch_1323
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.640
hpf
Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
  
    0.553
Arch_1465
Hypothetical protein; InterPro IPR008979; KEGG: pac:PPA1821 putative sialidase; SPTR: Q6A6R6 Putative sialidase.
       0.533
Arch_1322
COGs: COG3634 Alkyl hydroperoxide reductase large subunit; InterProIPR012081:IPR002109:IPR013027:IPR012335:IPR 012336:IPR000103:IPR008255; KEGG: nar:Saro_1718 pyridine nucleotide-disulphide oxidoreductase, class-II, active site; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Q3KC40 Alkyl hydroperoxide reductase subunit; TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: alkyl hydroperoxide reductase, F subunit.
 
  
 0.511
Arch_0748
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.455
Arch_1464
Coagulation factor 5/8 type domain protein; InterPro IPR000421:IPR008979; KEGG: coc:Coch_0195 glycoside hydrolase family 2 TIM barrel; PFAM: coagulation factor 5/8 type domain protein; SPTR: A3TGR0 Putative membrane protein; PFAM: F5/8 type C domain.
       0.433
Arch_0134
InterPro IPR006121:IPR017969; KEGG: mlu:Mlut_21360 copper chaperone; PFAM: Heavy metal transport/detoxification protein; SPTR: C0W4J0 MerTP family Hg2+ permease, binding protein; PFAM: Heavy-metal-associated domain.
  
  
 0.411
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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