STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1487Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917:IPR017849:IPR017850; KEGG: bfa:Bfae_28950 arylsulfatase A family protein; PFAM: sulfatase; SPTR: C0W1U3 Sulfatase; PFAM: Sulfatase. (473 aa)    
Predicted Functional Partners:
Arch_1490
Radical SAM domain protein; COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: tmz:Tmz1t_1479 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: D0YU66 Anaerobic sulfatase-maturating enzyme; PFAM: Radical SAM superfamily.
 
 
 0.885
Arch_1205
Radical SAM domain protein; COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197; KEGG: tte:TTE2358 Fe-S oxidoreductase; PFAM: Radical SAM domain protein; SPTR: C2GIA8 Radical SAM domain protein; PFAM: Radical SAM superfamily.
 
 
 0.741
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
   
    0.712
Arch_1488
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sth:STH770 LacI family transcriptional repressor; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W1U4 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family.
 
     0.688
Arch_1292
LPXTG-motif cell wall anchor domain protein; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR000421:IPR006104:IPR006102:IPR006103:IPR 011081:IPR011080:IPR013781:IPR019931:IPR017853:IPR008979:I PR006101; KEGG: apv:Apar_0102 glycoside hydrolase family 2 sugar binding; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; Ig domain protein; coagulation factor 5/8 type domain protein; SPTR: A4K5H9 Beta-galactosidase BbgIII; TIGRFAM: LPXTG-motif cell wall anchor dom [...]
 
 
 0.585
Arch_0628
LPXTG-motif cell wall anchor domain protein; COGs: COG4886 Leucine-rich repeat (LRR) protein; InterPro IPR007331:IPR019931; KEGG: pac:PPA0779 putative for Fe-transport; PFAM: Htaa domain protein; SPTR: C0W1M4 Putative uncharacterized protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Htaa.
 
     0.518
Arch_0050
Microcystin LR degradation protein MlrC; COGs: COG5476 conserved hypothetical protein; InterPro IPR015995:IPR010799:IPR009197; KEGG: pac:PPA2061 hypothetical protein; PFAM: Microcystin LR degradation protein MlrC-like; MlrC domain protein; SPTR: Q6A639 Conserved protein; PFAM: MlrC C-terminus; Protein of unknown function (DUF1485).
  
     0.492
Arch_1489
General substrate transporter; COGs: COG2814 Arabinose efflux permease; InterPro IPR005828:IPR016196:IPR005829; KEGG: kpn:KPN_03142 putative general substrate transporter; PFAM: General substrate transporter; SPTR: C0W1U5 Major facilitator family protein transporter; PFAM: Sugar (and other) transporter.
  
     0.485
Arch_0057
COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933:IPR013781:IPR016286:IPR017853; KEGG: pac:PPA2070 alpha-L-fucosidase precursor; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); PRIAM: Alpha-L-fucosidase; SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Q6A632 Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase.
 
   
 0.478
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.458
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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