STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Arch_1502PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: kra:Krad_1118 PfkB domain protein; PFAM: PfkB domain protein; SPTR: A6W717 PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (315 aa)    
Predicted Functional Partners:
Arch_0036
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: bcv:Bcav_1099 fructokinase; PFAM: PfkB domain protein; SPTR: C1RNV6 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase.
  
  
 
0.922
Arch_0377
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR013781:IPR006047:IPR006589:IPR017853; KEGG: cdi:DIP0532 putative amylase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Q6NJ80 Putative amylase; PFAM: Alpha amylase, catalytic domain.
 
 
 0.921
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.912
Arch_1291
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.912
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: pac:PPA2131 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: D0WNS5 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.910
Arch_0332
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR006148; KEGG: xce:Xcel_1049 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: D0WNV6 Glucosamine-6-phosphate deaminase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase.
  
 
 0.909
Arch_1620
Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterProIPR018050:IPR011051:IPR016305:IPR001250:IPR 014710; KEGG: bcv:Bcav_0860 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: D0WJT2 Mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
    
 0.905
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.901
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.789
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.783
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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