STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (222 aa)    
Predicted Functional Partners:
Arch_0211
methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579:IPR011057; KEGG: bcv:Bcav_3481 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: D1BE41 Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase.
 
 0.997
Arch_1554
Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
   
 0.994
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.900
Arch_0115
Glutaredoxin-like protein NrdH; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR012335:IPR011909:IPR012336; KEGG: bcv:Bcav_0095 glutaredoxin-like protein NrdH; PFAM: glutaredoxin; SPTR: D0WKQ6 Glutaredoxin; TIGRFAM: glutaredoxin-like protein NrdH; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein NrdH.
  
 
 0.826
greA
GreA/GreB family elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.810
Arch_1507
COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: bcv:Bcav_1060 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WQ01 Peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
       0.616
Arch_1810
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
     
 0.558
Arch_1504
Channel protein, hemolysin III family; COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254:IPR005744; KEGG: xce:Xcel_2630 Hly-III family protein; PFAM: Hly-III family protein; SPTR: D0WPZ5 Channel protein, hemolysin III family; TIGRFAM: channel protein, hemolysin III family; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family.
     
 0.552
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
  
  
 0.470
Arch_0748
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.458
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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