STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1513COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: aau:AAur_1266 putative exopolyphosphatase (ppx); PFAM: Ppx/GppA phosphatase; SPTR: D0WQ07 Phosphatase, Ppx/GppA family; PFAM: Ppx/GppA phosphatase family. (318 aa)    
Predicted Functional Partners:
Arch_1514
Protein of unknown function DUF501; COGs: COG1507 conserved hypothetical protein; InterPro IPR007511; KEGG: jde:Jden_1921 protein of unknown function DUF501; PFAM: protein of unknown function DUF501; SPTR: D0WQ08 Septum formation initiator family protein; PFAM: Protein of unknown function (DUF501).
 
    0.987
Arch_0828
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.937
Arch_1515
Septum formation initiator; InterPro IPR007060; KEGG: bcv:Bcav_1019 septum formation initiator; PFAM: Septum formation initiator; SPTR: D0WQ09 Putative membrane protein; PFAM: Septum formation initiator.
  
  
 0.885
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
 
    0.593
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.563
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.530
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
     
 0.521
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.493
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.493
Arch_1345
ROK family protein; InterPro IPR000600; KEGG: xce:Xcel_0657 ROK family protein; PFAM: ROK family protein; SPTR: D0WP77 ROK protein; manually curated; PFAM: ROK family.
 
   
 0.447
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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