STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1513COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: aau:AAur_1266 putative exopolyphosphatase (ppx); PFAM: Ppx/GppA phosphatase; SPTR: D0WQ07 Phosphatase, Ppx/GppA family; PFAM: Ppx/GppA phosphatase family. (318 aa)    
Predicted Functional Partners:
Arch_1514
Protein of unknown function DUF501; COGs: COG1507 conserved hypothetical protein; InterPro IPR007511; KEGG: jde:Jden_1921 protein of unknown function DUF501; PFAM: protein of unknown function DUF501; SPTR: D0WQ08 Septum formation initiator family protein; PFAM: Protein of unknown function (DUF501).
 
    0.986
Arch_0828
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.942
Arch_1515
Septum formation initiator; InterPro IPR007060; KEGG: bcv:Bcav_1019 septum formation initiator; PFAM: Septum formation initiator; SPTR: D0WQ09 Putative membrane protein; PFAM: Septum formation initiator.
  
  
 0.872
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.603
aroK
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
 
    0.600
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
       0.484
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
     
 0.476
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.447
Arch_1345
ROK family protein; InterPro IPR000600; KEGG: xce:Xcel_0657 ROK family protein; PFAM: ROK family protein; SPTR: D0WP77 ROK protein; manually curated; PFAM: ROK family.
 
   
 0.419
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.