STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1549Peptidase S14 ClpP; COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: det:DET1086 ATP-dependent Clp protease, proteolytic subunit ClpP, putative; PFAM: peptidase S14 ClpP; SPTR: C8RU57 ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: Clp protease; Belongs to the peptidase S14 family. (277 aa)    
Predicted Functional Partners:
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
0.978
Arch_1550
Phage portal protein, HK97 family; COGs: COG4695 Phage-related protein; InterPro IPR006944:IPR006427; KEGG: det:DET1087 HK97 family portal protein, putative; PFAM: portal protein; SPTR: C2KNX2 HK97 family portal protein; TIGRFAM: phage portal protein, HK97 family; PFAM: Phage portal protein; TIGRFAM: phage portal protein, HK97 family.
 
    0.956
Arch_1548
COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; InterPro IPR006444; KEGG: tex:Teth514_1254 HK97 family phage major capsid protein; PFAM: major capsid protein HK97; SPTR: C8RU58 HK97 family major capsid protein; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; TIGRFAM: phage major capsid protein, HK97 family.
 
    0.936
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 
 0.935
Arch_0523
Portal protein; COGs: COG4695 Phage-related protein; InterPro IPR006944; KEGG: tex:Teth514_1252 HK97 family phage portal protein; PFAM: portal protein; SPTR: C2KNX2 HK97 family portal protein; PFAM: Phage portal protein; TIGRFAM: phage portal protein, HK97 family.
 
    0.812
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.785
Arch_0227
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489:IPR001270:IPR018368; KEGG: xce:Xcel_0363 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: D0WM50 Negative regulator of genetic competence ClpC/MecB; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various c [...]
  
 
 0.785
Arch_0519
DNA methylase N-4/N-6 domain protein; COGs: COG0863 DNA modification methylase; InterProIPR002052:IPR002295:IPR003115:IPR002941:IPR 015840; KEGG: pac:PPA1586 ParB family DNA methylase; PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: C2KNX9 ParB family DNA methylase; manually curated; PFAM: ParB-like nuclease domain; DNA methylase.
 
   
 0.751
Arch_1546
KEGG: tex:Teth514_1257 phage head-tail adaptor, putative; SPTR: C8RU60 Phage head-tail adaptor; PFAM: Phage head-tail joining protein.
 
    0.725
Arch_0111
Oligopeptidase B; COGs: COG1770 Protease II; InterPro IPR004106:IPR001375:IPR002470; KEGG: bfa:Bfae_03460 oligopeptidase B; PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; PRIAM: Oligopeptidase B; SPTR: D0WKS9 Protease II; PFAM: Prolyl oligopeptidase, N-terminal beta-propeller domain; Prolyl oligopeptidase family.
   
  
 0.720
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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