STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Arch_1580N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356; KEGG: dvl:Dvul_0488 N-6 DNA methylase; PFAM: N-6 DNA methylase; SPTR: C8RRG5 Type I restriction-modification system, M subunit N-6 adenine-specific DNA methylase; PFAM: N-6 DNA Methylase; HsdM N-terminal domain. (231 aa)    
Predicted Functional Partners:
Arch_1052
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: vei:Veis_1015 restriction modification system DNA specificity subunit; PFAM: restriction modification system DNA specificity domain; SPTR: B2N0G8 Putative type I restriction-modification system, S subunit; PFAM: Type I restriction modification DNA specificity domain.
  
 
 0.909
Arch_1051
Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: bpt:Bpet3989 type I restriction-modification system, S subunit; PFAM: restriction modification system DNA specificity domain; SPTR: A9I6S0 Type I restriction-modification system, S subunit; manually curated; PFAM: Type I restriction modification DNA specificity domain.
  
 
 0.870
Arch_1581
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.781
Arch_1054
COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR014021:IPR001650:IPR014001:IPR007409:IPR 006935:IPR013670; KEGG: pnu:Pnuc_1134 EcoEI R domain-containing protein; PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; helicase domain protein; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase; SPTR: A4SXY6 EcoEI R, C-terminal domain protein; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); EcoEI R protein C-terminal; Type II [...]
  
 
 0.688
Arch_1579
KEGG: cai:Caci_5930 hypothetical protein; SPTR: C2GDL7 Putative uncharacterized protein; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
       0.665
Arch_0519
DNA methylase N-4/N-6 domain protein; COGs: COG0863 DNA modification methylase; InterProIPR002052:IPR002295:IPR003115:IPR002941:IPR 015840; KEGG: pac:PPA1586 ParB family DNA methylase; PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: C2KNX9 ParB family DNA methylase; manually curated; PFAM: ParB-like nuclease domain; DNA methylase.
  
  
 0.431
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.429
Arch_1582
KEGG: dda:Dd703_3047 site-specific DNA-methyltransferase (adenine-specific); SPTR: C6CCH7 Site-specific DNA-methyltransferase (Adenine-specific).
     
 0.423
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.