STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1610COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: jde:Jden_1969 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: D0WJR1 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase. (205 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.923
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR020825:IPR005121:IPR016027:IPR009061:IPR 004532:IPR002547:IPR012340:IPR005147:IPR005146; KEGG: jde:Jden_1109 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: D0WN31 Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synt [...]
 
  
 0.656
Arch_1611
SAF domain protein; InterPro IPR013974; KEGG: bcv:Bcav_0901 SAF domain protein; PFAM: SAF domain protein; SPTR: D0WJR4 Flp pilus assembly protein CpaB family protein; PFAM: SAF domain; TIGRFAM: Flp pilus assembly protein CpaB.
 
     0.616
Arch_1609
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
       0.588
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.576
Arch_0097
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: jde:Jden_0165 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: A7BB19 Putative uncharacterized protein; PFAM: Rhomboid family.
  
  
 0.561
Arch_1246
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: car:cauri_1058 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: A7BBB8 Putative uncharacterized protein; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
     
 0.505
Arch_0770
KEGG: bcv:Bcav_1933 DNA-binding protein; SPTR: D0WQI5 Putative DNA-binding protein; PFAM: Protein of unknown function (DUF3071).
 
     0.502
Arch_1515
Septum formation initiator; InterPro IPR007060; KEGG: bcv:Bcav_1019 septum formation initiator; PFAM: Septum formation initiator; SPTR: D0WQ09 Putative membrane protein; PFAM: Septum formation initiator.
  
     0.420
Arch_0676
COGs: COG1589 Cell division septal protein; KEGG: jde:Jden_1076 polypeptide-transport-associated domain protein FtsQ-type; SPTR: D0WQV7 Cell division protein FtsQ-like protein; PFAM: Cell division protein FtsQ.
  
   
 0.410
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (14%) [HD]