STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1619COGs: COG2252 Permease; InterPro IPR006043; KEGG: kra:Krad_1382 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: D0WJT1 Xanthine/uracil permease family protein; PFAM: Permease family. (490 aa)    
Predicted Functional Partners:
Arch_1655
COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR006042; KEGG: bcv:Bcav_0274 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: C2BTD4 NCS2 family nucleobase:cation symporter-2; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease.
 
  
 0.733
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.689
Arch_1673
COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease.
 
  
 0.650
Arch_1621
KEGG: kra:Krad_3581 hypothetical protein; SPTR: D0WJT3 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3027).
       0.637
Arch_1622
Cold-shock DNA-binding domain protein; COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR016027:IPR002059:IPR012340; KEGG: bcv:Bcav_0848 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: D0WJT4 Cold-shock domain protein; PFAM: 'Cold-shock' DNA-binding domain.
       0.637
Arch_1620
Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterProIPR018050:IPR011051:IPR016305:IPR001250:IPR 014710; KEGG: bcv:Bcav_0860 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: D0WJT2 Mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
       0.593
Arch_0791
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: chy:CHY_1069 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: Q3AD69 Phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase.
  
    0.486
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
  
  
 0.483
purC
COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR013816:IPR010916; KEGG: mlu:Mlut_18500 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: D0WLR3 Phosphoribosylaminoimidazolesuccinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
  
  
 0.470
Arch_1618
Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR008988:IPR007167:IPR011991; KEGG: jde:Jden_1989 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: C7R0G3 Iron (Metal) dependent repressor, DtxR family; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain.
  
    0.455
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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