STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Arch_1638H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: krh:KRH_15110 putative cation transporter; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: C2BVK7 Possible H(+)-transporting two-sector ATPase; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family. (456 aa)    
Predicted Functional Partners:
Arch_1639
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037; KEGG: sro:Sros_6144 TrkA-N; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0YQI4 TrkA-N; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.969
Arch_0277
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037:IPR016040; KEGG: bcv:Bcav_3270 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0WME1 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.895
Arch_0859
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: jde:Jden_1312 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: D0WMY6 Ribosomal RNA small subunit methyltransferase B; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.569
Arch_0775
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036:IPR016040:IPR003148:IPR006037; KEGG: bcv:Bcav_1941 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: D0WQH9 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.547
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
       0.538
Arch_1637
Alcohol dehydrogenase GroES domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterProIPR002328:IPR011032:IPR016040:IPR013154:IPR 013149; KEGG: kse:Ksed_10170 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: C0W4J4 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: L-threonine 3-dehydrogenase.
       0.538
Arch_0776
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR016040:IPR003148:IPR006037; KEGG: jde:Jden_1405 TrkA-N domain protein; PFAM: TrkA-N domain protein; SPTR: D0WQH8 Trk-type K+ transport system, NAD-binding component; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.530
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.442
Arch_0148
Multisubunit sodium/proton antiporter, MrpB subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750:IPR007182:IPR003916; KEGG: bcv:Bcav_3818 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); Na+/H+ antiporter MnhB subunit-related protein; SPTR: C5C4D6 NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; Domain related to MnhB subunit of Na+/H+ antiporter; 2.A.63.1.
     
 0.434
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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