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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1664Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR016032:IPR001867; KEGG: mlu:Mlut_03750 PhoP-like protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C0W5A5 Response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (229 aa)    
Predicted Functional Partners:
Arch_1665
Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR009082:IPR005467:IPR 004358; KEGG: bcv:Bcav_0770 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C5BYS3 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 0.997
Arch_0642
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR009082:IPR003661:IPR 005467; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C2KNB8 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.892
Arch_1131
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR003661:IPR 004358; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: D1BZA0 Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.882
Arch_1627
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR009082:IPR 005467:IPR004358; KEGG: kra:Krad_3621 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WJT8 PhoR protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoaccept [...]
 
 0.858
Arch_1418
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1241 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: D0WPH4 Sensor histidine kinase MtrB; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.834
Arch_1428
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1156 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WPL5 Putative two-component system histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.716
Arch_1666
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.679
Arch_0898
Response regulator receiver and ANTAR domain protein; COGs: COG3707 Response regulator with putative antiterminator output domain; InterProIPR011006:IPR001789:IPR008327:IPR005561:IPR 011991; KEGG: bfa:Bfae_14950 response regulator with putative antiterminator output domain; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: D0WMQ2 Two-component system response regulator; PFAM: Response regulator receiver domain; ANTAR domain.
  
   
 0.638
Arch_1663
COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: ace:Acel_0078 CarD family transcriptional regulator; PFAM: transcription factor CarD; SPTR: D0WJY8 Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain.
  
  
 0.590
Arch_0299
NADH-quinone oxidoreductase, chain G; COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterProIPR001041:IPR019574:IPR006656:IPR010228:IPR 000283; KEGG: xce:Xcel_0475 NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molybdopterin oxidoreductase; SPTR: D0WMG7 NADH dehydrogenase, G subunit; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; TIG [...]
    
 
 0.456
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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