STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1665Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR009082:IPR005467:IPR 004358; KEGG: bcv:Bcav_0770 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C5BYS3 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (393 aa)    
Predicted Functional Partners:
Arch_1664
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR016032:IPR001867; KEGG: mlu:Mlut_03750 PhoP-like protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C0W5A5 Response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 0.997
Arch_1666
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
   
 0.941
Arch_1130
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR000463:IPR001867; KEGG: xce:Xcel_2992 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0YTJ0 Transcriptional regulatory protein ResD; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.894
Arch_1419
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: mva:Mvan_1752 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0WPH5 DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.884
Arch_0641
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR011991:IPR001867; KEGG: xce:Xcel_2992 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D1BZA1 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.875
Arch_1429
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: bcv:Bcav_1155 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: A7B947 Putative uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.875
Arch_1626
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR001867; KEGG: xce:Xcel_2937 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0WJT7 DNA-binding response regulator PhoP; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.872
Arch_0215
Phosphate ABC transporter, periplasmic phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
  
  
 0.639
Arch_0217
Phosphate ABC transporter, inner membrane subunit PstA; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: bcv:Bcav_3424 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C5C241 Phosphate ABC transporter, inner membrane subunit PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA.
 
   
 0.606
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
   
 0.588
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.