| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Arch_1278 | Arch_1672 | Arch_1278 | Arch_1672 | Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase. | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | 0.649 |
| Arch_1278 | thiM | Arch_1278 | Arch_1280 | Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.999 |
| Arch_1672 | Arch_1278 | Arch_1672 | Arch_1278 | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase. | 0.649 |
| Arch_1672 | Arch_1673 | Arch_1672 | Arch_1673 | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | 0.699 |
| Arch_1672 | carB | Arch_1672 | Arch_1024 | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | 0.487 |
| Arch_1672 | pyrB | Arch_1672 | Arch_1019 | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | 0.555 |
| Arch_1672 | thiM | Arch_1672 | Arch_1280 | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.422 |
| Arch_1673 | Arch_1672 | Arch_1673 | Arch_1672 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | 0.699 |
| Arch_1673 | carB | Arch_1673 | Arch_1024 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | 0.732 |
| Arch_1673 | pyrB | Arch_1673 | Arch_1019 | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | 0.773 |
| carB | Arch_1672 | Arch_1024 | Arch_1672 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | 0.487 |
| carB | Arch_1673 | Arch_1024 | Arch_1673 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | 0.732 |
| carB | pyrB | Arch_1024 | Arch_1019 | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | 0.999 |
| pyrB | Arch_1672 | Arch_1019 | Arch_1672 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | 0.555 |
| pyrB | Arch_1673 | Arch_1019 | Arch_1673 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043:IPR018020:IPR017588; KEGG: cdi:DIP1943 xanthine/uracil permeases family protein; PFAM: Xanthine/uracil/vitamin C permease; Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SPTR: Q6NFE8 Xanthine/uracil permeases family protein; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: OHCU decarboxylase; Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease. | 0.773 |
| pyrB | carB | Arch_1019 | Arch_1024 | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130:IPR002082:IPR006132:IPR006131; KEGG: cpf:CPF_1387 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: C2KYS1 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Aspartate carbamoyltransferase regulatory c [...] | COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR016185:IPR005480:IPR006275:IPR011761:IPR 005479:IPR013817:IPR013816:IPR005481:IPR011607:IPR005483; KEGG: gwc:GWCH70_1047 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: B6FK85 Putative uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, [...] | 0.999 |
| thiM | Arch_1278 | Arch_1280 | Arch_1278 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase. | 0.999 |
| thiM | Arch_1672 | Arch_1280 | Arch_1672 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Permease for cytosine/purines uracil thiamine allantoin; COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bfa:Bfae_30600 purine-cytosine permease-like transporter; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: C7MAT4 Purine-cytosine permease-like transporter; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; Belongs to the purine-cytosine permease (2.A.39) family. | 0.422 |