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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1678Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR011010:IPR010998:IPR002104:IPR013762; KEGG: mpa:MAP2752 hypothetical protein; PFAM: integrase family protein; SPTR: B5U3A1 Gp33; PFAM: Phage integrase family. (260 aa)    
Predicted Functional Partners:
Arch_1679
Cobyrinic acid ac-diamide synthase; COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: ach:Achl_4190 cobyrinic acid ac-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: C2BRF7 Chromosome partitioning protein transcriptional regulator; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
   
 0.825
Arch_0644
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: kra:Krad_1482 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: D0WR03 FtsK/SpoIIIE family protein; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
 
   
 0.710
Arch_1680
Hypothetical protein; KEGG: pis:Pisl_0752 small GTP-binding protein; SPTR: C2BRF8 Putative uncharacterized protein.
       0.680
Arch_1416
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: bcv:Bcav_1243 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: D0WPH2 Competence protein F; PFAM: Phosphoribosyl transferase domain.
   
    0.463
apt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.461
Arch_0939
NUDIX hydrolase; InterPro IPR015797:IPR000086; KEGG: xce:Xcel_1348 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WMJ2 MutT/NUDIX family protein; PFAM: NUDIX domain.
  
  
 0.460
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.419
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
   
    0.414
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.407
xerC
Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
    
0.404
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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