STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1701TAP domain protein; InterPro IPR000073:IPR013595; KEGG: xce:Xcel_0356 TAP domain protein; PFAM: TAP domain protein; alpha/beta hydrolase fold; SPTR: D0WK12 Putative uncharacterized protein; PFAM: TAP-like protein. (520 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.794
Arch_1702
COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: xce:Xcel_0355 DNA polymerase III, delta prime subunit; SPTR: D1BVC3 DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit.
  
    0.783
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.781
Arch_1705
Methyltransferase small; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR002052:IPR007848; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: C7NG68 Methyltransferase family protein; PFAM: Methyltransferase small domain; Belongs to the methyltransferase superfamily.
  
    0.557
Arch_1363
COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR013786:IPR 013764:IPR009100:IPR009075; KEGG: drm:Dred_0570 crotonobetainyl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: D0WP06 Crotonobetainyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
   
 0.529
Arch_0239
LPXTG-motif cell wall anchor domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334:IPR019931:IPR006179; KEGG: cgt:cgR_0412 hypothetical protein; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: D0WQ91 5-nucleotidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: 5'-nucleotidase, C-terminal domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
   
  
 0.490
Arch_0799
KEGG: bcv:Bcav_1965 hypothetical protein; SPTR: D0WQH2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3000).
  
     0.426
Arch_0393
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase.
 
    0.406
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.