STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1711KEGG: bad:BAD_0132 hypothetical protein; SPTR: D0WK38 Putative uncharacterized protein. (64 aa)    
Predicted Functional Partners:
Arch_1709
Hypothetical protein; InterPro IPR019793; KEGG: rha:RHA1_ro04345 hypothetical protein; SPTR: Q0S8K1 Putative uncharacterized protein.
       0.569
Arch_1710
KEGG: rop:ROP_42540 hypothetical membrane protein; SPTR: C1B9Z8 Hypothetical membrane protein.
       0.569
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.493
Arch_1228
Type II secretion system protein E; COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: fra:Francci3_0779 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: A3TG68 Putative type II/type IV pathway secretion protein; PFAM: Type II/IV secretion system protein.
     
 0.439
Arch_1716
Type II secretion system protein E; COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: bcv:Bcav_0619 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: D0WK43 Pilus assembly protein CpaF; PFAM: Type II/IV secretion system protein.
     
 0.439
Arch_1712
Hypothetical protein.
       0.413
Arch_1714
KEGG: bcv:Bcav_0621 type II secretion system protein; SPTR: D0WK41 Putative integral membrane protein.
     
 0.413
Arch_1715
KEGG: bcv:Bcav_0620 hypothetical protein; SPTR: D0WK42 Type II secretion system protein.
     
 0.413
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.