STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1727Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR005543:IPR001264:IPR001460; KEGG: bcv:Bcav_0604 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WK60 Penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; PASTA domain. (800 aa)    
Predicted Functional Partners:
Arch_1728
Metallophosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: bcv:Bcav_0603 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: D0WK61 Ser/Thr protein phosphatase family protein; PFAM: Calcineurin-like phosphoesterase.
       0.857
Arch_0673
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018488:IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: D0WQN1 Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
 
 
 0.815
Arch_0103
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460:IPR012338; KEGG: jde:Jden_0172 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; SPTR: D0WKX2 Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.
 
 
 
0.778
Arch_0668
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR012338:IPR005311:IPR001460; KEGG: bcv:Bcav_2416 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WQW3 Penicillin binding protein transpeptidase domain protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
 
 
 
 0.778
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
   
 0.718
Arch_0681
DivIVA domain protein; InterPro IPR019933:IPR007793; KEGG: xce:Xcel_1291 DivIVA family protein; PFAM: DivIVA family protein; SPTR: D0WQV0 Cell division protein, DivIVA family; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain.
   
 
 0.649
Arch_0373
KEGG: xce:Xcel_2425 hypothetical protein; SPTR: D0WRU4 Putative cellulose-binding protein; PFAM: DivIVA protein.
 
 
 
 0.644
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.632
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.626
whiB-4
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
     
 0.623
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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