STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1738ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR018303:IPR001757:IPR000695:IPR008250:IPR 005834; KEGG: mab:MAB_0962 cation-transporting ATPase E; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: D0WK77 Cation-transporting ATPase, E1-E2 family; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC. (786 aa)    
Predicted Functional Partners:
Arch_1160
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: bcv:Bcav_0823 MgtC/SapB transporter; PFAM: MgtC/SapB transporter; SPTR: D0WQ67 MgtC/SapB transporter; PFAM: MgtC family.
 
 
 0.718
Arch_1739
Domain of unknown function DUF1846; COGs: COG4868 conserved hypothetical protein; InterPro IPR014999; KEGG: cur:cur_0538 hypothetical protein; PFAM: Domain of unknown function DUF1846; SPTR: B1VFF9 UPF0371 protein cu0538; PFAM: Domain of unknown function (DUF1846); Belongs to the UPF0371 family.
       0.709
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.642
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.465
Arch_1015
Peptidase S8 and S53 subtilisin kexin sedolisin; InterPro IPR000209:IPR003137:IPR010435; KEGG: bfa:Bfae_23940 subtilisin-like serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; protein of unknown function DUF1034; SPTR: C7MFG9 Subtilisin-like serine protease; PFAM: PA domain; Fn3-like domain (DUF1034); Subtilase family; Belongs to the peptidase S8 family.
  
 
 0.447
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.444
Arch_0133
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757:IPR018303:IPR017969:IPR000150; KEGG: jde:Jden_2501 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: D0WKF6 Copper-exporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy [...]
 
 
0.402
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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