STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa)    
Predicted Functional Partners:
Arch_0264
ATP-binding protein; COGs: COG0572 Uridine kinase; KEGG: bcv:Bcav_3297 ATP-binding protein; SPTR: C5C1D0 ATP-binding protein.
  
 0.978
Arch_1266
COGs: COG0213 Thymidine phosphorylase; InterProIPR000053:IPR017459:IPR000312:IPR013102:IPR 020072:IPR018090:IPR017872; KEGG: car:cauri_1882 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like; PRIAM: Thymidine phosphorylase; SPTR: C3PI21 Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
  
 
 0.961
udk
COGs: COG0572 Uridine kinase; InterPro IPR006083:IPR000764:IPR017975; KEGG: cbt:CLH_0992 uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SPTR: D0WPE8 Uridine kinase; TIGRFAM: uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase.
  
 0.961
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.950
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.948
Arch_1262
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.940
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.935
Arch_1005
COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845; KEGG: kse:Ksed_10970 purine-nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: C0W1W4 Purine nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
    
  0.907
Arch_0025
5'-Nucleotidase domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334:IPR006179; KEGG: mxa:MXAN_5361 putative 5'-nucleotidase; PFAM: 5'-Nucleotidase domain protein; SPTR: A8TK86 5'-Nucleotidase; PFAM: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
     
 0.900
Arch_0203
LPXTG-motif cell wall anchor domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334:IPR019931:IPR006179; KEGG: cjk:jk1044 putative 5'-nucleotidase family protein; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: Q4JVE9 Putative 5'-nucleotidase family protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: LPXTG-motif cell wall anchor domain; Belongs to the 5'-nucleotidase family.
     
 0.900
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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