STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1747KEGG: bcv:Bcav_0374 hypothetical protein; SPTR: D0WK91 Putative uncharacterized protein. (285 aa)    
Predicted Functional Partners:
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR009008:IPR009080:IPR002302:IPR001412:IPR 014729:IPR002300:IPR013155; KEGG: bcv:Bcav_1730 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; SPTR: D0WN91 Leucine--tRNA ligase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); tRNA synthetases class I (M); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family.
 
     0.716
Arch_0328
KEGG: bcv:Bcav_1264 DoxX family protein; SPTR: D0WRQ0 DoxX family protein.
  
     0.670
Arch_0895
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: xce:Xcel_1513 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: D0WMQ5 SAM-dependent methyltransferase; PFAM: Methyltransferase domain.
  
     0.582
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.555
Arch_1746
Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: bcv:Bcav_0467 hypothetical protein; PFAM: alpha/beta hydrolase fold; SPTR: D0WK88 Hydrolase, alpha/beta fold family domain protein; PFAM: alpha/beta hydrolase fold.
       0.546
Arch_0208
InterPro IPR009937; KEGG: bcv:Bcav_3512 protein of unknown function DUF1469; PFAM: protein of unknown function DUF1469; SPTR: C0VYT0 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1469).
 
     0.539
Arch_1748
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bcv:Bcav_0375 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: D0WK92 Glycosyltransferase, group 2 family; PFAM: Glycosyl transferase family 2.
       0.539
Arch_0561
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: jde:Jden_0984 amidohydrolase; PFAM: amidohydrolase; SPTR: Q8VVP7 Putative uncharacterized protein; manually curated.
  
     0.516
Arch_1250
thiamineS protein; InterPro IPR016155:IPR012675:IPR003749; KEGG: fre:Franean1_6174 thiamineS protein; PFAM: thiamineS protein; SPTR: D0WL89 Molybdopterin converting factor, subunit 1; PFAM: ThiS family.
  
     0.478
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.475
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.