STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1760CRISPR-associated protein, Cse3 family; InterPro IPR010179; KEGG: cdi:DIP2212 hypothetical protein; PFAM: CRISPR-associated protein CT1974; SPTR: Q6NEQ5 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family. (232 aa)    
Predicted Functional Partners:
Arch_1757
CRISPR-associated protein, Cse4 family; InterPro IPR010148; KEGG: cdi:DIP2209 hypothetical protein; PFAM: CRISPR-associated protein CT1975; SPTR: Q6NEQ8 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family.
 
 
 0.999
Arch_1761
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR014001:IPR001650:IPR006474; KEGG: cdi:DIP2213 putative helicase; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q6NEQ4 Putative helicase; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; CRISPR-associated helicase Cas3.
 
 
 
 0.999
Arch_1756
CRISPR-associated protein Cas5 family; InterPro IPR010147:IPR013422; KEGG: cdi:DIP2208 hypothetical protein; PFAM: CRISPR-associated protein CT1976; SPTR: Q6NEQ9 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5, Ecoli subtype.
 
 
 0.995
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.969
Arch_1759
KEGG: cdi:DIP2211 hypothetical protein; SPTR: Q6NEQ6 Putative uncharacterized protein; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family.
   
 
 0.962
Arch_1763
CRISPR-associated protein Cas2; InterPro IPR010152; KEGG: cdi:DIP2215 hypothetical protein; PFAM: CRISPR-associated protein Cas2; SPTR: Q6NEQ2 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated protein Cas2, E. coli subfamily.
 
  
 0.949
Arch_0617
LPXTG-motif cell wall anchor domain protein; InterPro IPR005519:IPR019931; KEGG: cai:Caci_5772 acid phosphatase (class B); PFAM: acid phosphatase (Class B); SPTR: B5HR56 Secreted protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: HAD superfamily, subfamily IIIB (Acid phosphatase); TIGRFAM: LPXTG-motif cell wall anchor domain.
  
     0.677
Arch_1798
Glycoside hydrolase family 85; COGs: COG4724 Endo-beta-N-acetylglucosaminidase D; InterPro IPR008957:IPR003961:IPR005201; KEGG: pac:PPA1805 endo-beta-N-acetylglucosaminidase family protein; PFAM: glycoside hydrolase family 85; Fibronectin type III domain protein; SPTR: Q6A6T2 Endo-beta-N-acetylglucosaminidase family protein; PFAM: Glycosyl hydrolase family 85; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
     0.669
Arch_0242
KEGG: xce:Xcel_3007 hypothetical protein; SPTR: A7BBM1 Putative uncharacterized protein.
  
     0.626
Arch_1180
InterPro IPR009057:IPR001647:IPR012287; KEGG: cjk:jk0810 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C5VD50 Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.624
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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