STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (327 aa)    
Predicted Functional Partners:
Arch_1763
CRISPR-associated protein Cas2; InterPro IPR010152; KEGG: cdi:DIP2215 hypothetical protein; PFAM: CRISPR-associated protein Cas2; SPTR: Q6NEQ2 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated protein Cas2, E. coli subfamily.
 
 
 0.999
Arch_1760
CRISPR-associated protein, Cse3 family; InterPro IPR010179; KEGG: cdi:DIP2212 hypothetical protein; PFAM: CRISPR-associated protein CT1974; SPTR: Q6NEQ5 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family.
 
  
 0.969
Arch_1761
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR014001:IPR001650:IPR006474; KEGG: cdi:DIP2213 putative helicase; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Q6NEQ4 Putative helicase; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; CRISPR-associated helicase Cas3.
 
  
 0.969
Arch_1757
CRISPR-associated protein, Cse4 family; InterPro IPR010148; KEGG: cdi:DIP2209 hypothetical protein; PFAM: CRISPR-associated protein CT1975; SPTR: Q6NEQ8 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family.
 
  
 0.934
Arch_1756
CRISPR-associated protein Cas5 family; InterPro IPR010147:IPR013422; KEGG: cdi:DIP2208 hypothetical protein; PFAM: CRISPR-associated protein CT1976; SPTR: Q6NEQ9 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5, Ecoli subtype.
 
  
 0.920
Arch_1759
KEGG: cdi:DIP2211 hypothetical protein; SPTR: Q6NEQ6 Putative uncharacterized protein; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family.
  
  
 0.701
Arch_1758
CRISPR-associated protein, Cse2 family; InterPro IPR013382; KEGG: cdi:DIP2210 hypothetical protein; PFAM: CRISPR-associated protein Cse2; SPTR: Q6NEQ7 Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR-associated protein, Cse2 family.
       0.524
Arch_0750
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
     
 0.500
Arch_1119
COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR010992:IPR000119; KEGG: bcv:Bcav_2752 histone family protein DNA-binding protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: D0WNJ5 DNA-binding protein HU; PFAM: Bacterial DNA-binding protein; Belongs to the bacterial histone-like protein family.
    
   0.475
Arch_0042
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104:IPR016040; KEGG: pac:PPA0469 putative myo-inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: C0W6K5 Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
   
 
 0.416
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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