STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1767Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: ami:Amir_0404 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: C6WGQ5 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (227 aa)    
Predicted Functional Partners:
Arch_0044
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: msm:MSMEG_4659 GntR-family protein transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: C2KTD8 Transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
     0.763
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.705
Arch_1768
Sugar transporter; InterPro IPR005829:IPR016196:IPR003663:IPR005828; KEGG: mlu:Mlut_15770 MFS transporter, sugar porter family; PFAM: General substrate transporter; SPTR: Q0S1H0 Sugar transporter, MFS superfamily protein; TIGRFAM: sugar transporter; PFAM: Sugar (and other) transporter; TIGRFAM: MFS transporter, sugar porter (SP) family; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
       0.561
Arch_1769
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR000073:IPR013094; KEGG: ami:Amir_4661 alpha/beta hydrolase fold-3 domain protein; PFAM: Alpha/beta hydrolase fold-3 domain protein; alpha/beta hydrolase fold; SPTR: D0WQ59 Hydrolase, alpha/beta fold family; PFAM: alpha/beta hydrolase fold.
       0.496
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
 
  
 0.477
Arch_0333
COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680; KEGG: xce:Xcel_2442 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: D0WNV7 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase.
 
  
 0.473
Arch_0455
InterPro IPR010982; KEGG: cef:CE1210 putative transcription regulator; SPTR: Q8FQB1 Putative transcription regulator.
  
  
 0.444
Arch_0329
Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR011991:IPR000524:IPR011711; KEGG: bcv:Bcav_3776 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: D0WKM6 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
  
    0.432
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.425
Arch_1427
COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: bcv:Bcav_1165 cell envelope-related protein transcriptional attenuator; PFAM: cell envelope-related transcriptional attenuator; SPTR: D0WPL0 Transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
  
    0.422
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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