STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1774Domain of unknown function DUF1727; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR013221:IPR013564; KEGG: cur:cur_1907 putative UDP-N-acetylmuramyl tripeptide synthase; PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; SPTR: C2BT38 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain. (479 aa)    
Predicted Functional Partners:
Arch_1775
COGs: COG3442 glutamine amidotransferase; InterPro IPR017929:IPR011698; KEGG: gbr:Gbro_0441 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: C2BT37 Possible adenosylcobyric acid synthase, glutamine-hydrolyzing; PFAM: CobB/CobQ-like glutamine amidotransferase domain.
 0.999
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.954
Arch_0164
Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447:IPR016181; KEGG: apr:Apre_0286 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: C7RFS6 Methicillin resistance protein; PFAM: FemAB family.
 
 
 0.922
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
  
 0.626
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.556
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.554
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR020825:IPR005121:IPR016027:IPR009061:IPR 004532:IPR002547:IPR012340:IPR005147:IPR005146; KEGG: jde:Jden_1109 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: D0WN31 Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synt [...]
  
  
 0.435
Arch_0676
COGs: COG1589 Cell division septal protein; KEGG: jde:Jden_1076 polypeptide-transport-associated domain protein FtsQ-type; SPTR: D0WQV7 Cell division protein FtsQ-like protein; PFAM: Cell division protein FtsQ.
  
  
 0.433
Arch_0103
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460:IPR012338; KEGG: jde:Jden_0172 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; SPTR: D0WKX2 Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain.
  
  
 0.419
Arch_0668
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR012338:IPR005311:IPR001460; KEGG: bcv:Bcav_2416 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WQW3 Penicillin binding protein transpeptidase domain protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
  
  
 0.419
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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