STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1777Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: svi:Svir_38090 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having dd or ED; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C7MRG7 Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. (214 aa)    
Predicted Functional Partners:
Arch_1776
(Uracil-5)-methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: kra:Krad_4319 23S rRNA (uracil-5-)-methyltransferase RumB; PFAM: (Uracil-5)-methyltransferase; SPTR: A6WG43 23S rRNA (Uracil-5-)-methyltransferase RumB; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
    0.776
Arch_1778
Hypothetical protein.
       0.522
Arch_1016
KEGG: cdi:DIP2140 putative integral membrane protein; SPTR: Q6NEW9 Putative integral membrane protein; manually curated.
 
    0.481
Arch_0017
Transcriptional regulator, TetR family; InterPro IPR001647:IPR012287:IPR009057; KEGG: jde:Jden_0686 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: C0W4B6 Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
 
     0.466
Arch_0263
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: jde:Jden_0486 major intrinsic protein; PFAM: major intrinsic protein; SPTR: C2KN37 MIP family major intrinsic protein channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.456
Arch_0413
InterPro IPR003838; KEGG: bcv:Bcav_2825 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: C5V906 ABC transporter integral membrane protein; PFAM: Predicted permease.
 
     0.441
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
  
  
 0.429
Arch_0187
NUDIX hydrolase; InterPro IPR000086:IPR015797:IPR020476; KEGG: cgb:cg1303 NTP pyrophosphohydrolase; PFAM: NUDIX hydrolase; SPTR: Q8NR99 NTP pyrophosphohydrolases including oxidative damage repair enzymes; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein.
 
 
 0.408
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.