STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Arch_1777Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: svi:Svir_38090 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having dd or ED; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C7MRG7 Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. (214 aa)    
Predicted Functional Partners:
Arch_1776
(Uracil-5)-methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280; KEGG: kra:Krad_4319 23S rRNA (uracil-5-)-methyltransferase RumB; PFAM: (Uracil-5)-methyltransferase; SPTR: A6WG43 23S rRNA (Uracil-5-)-methyltransferase RumB; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
     0.775
Arch_0289
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254:IPR009003:IPR001940; KEGG: bcv:Bcav_3234 2-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: C5C0T2 2-alkenal reductase; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
  
 
  0.584
Arch_1778
Hypothetical protein.
       0.522
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.512
Arch_0263
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: jde:Jden_0486 major intrinsic protein; PFAM: major intrinsic protein; SPTR: C2KN37 MIP family major intrinsic protein channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.494
Arch_0426
Protein of unknown function DUF1212; COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: rmu:RMDY18_06380 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: C0W2A9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1212).
       0.493
Arch_1016
KEGG: cdi:DIP2140 putative integral membrane protein; SPTR: Q6NEW9 Putative integral membrane protein; manually curated.
 
  
 0.479
Arch_0017
Transcriptional regulator, TetR family; InterPro IPR001647:IPR012287:IPR009057; KEGG: jde:Jden_0686 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: C0W4B6 Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
 
   
 0.465
Arch_0413
InterPro IPR003838; KEGG: bcv:Bcav_2825 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: C5V906 ABC transporter integral membrane protein; PFAM: Predicted permease.
 
     0.440
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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