STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (407 aa)    
Predicted Functional Partners:
Arch_1134
Conserved hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
 
   
 0.806
Arch_0178
Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain protein; COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058:IPR014729:IPR020060:IPR001412; KEGG: mgi:Mflv_1233 glutamyl-Q tRNA(Asp) synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: D0WLH0 Glutamate--tRNA ligase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   
 0.742
Arch_1787
KEGG: fnu:FN1780 hypothetical protein; SPTR: D0WLC6 Putative uncharacterized protein.
       0.731
Arch_1788
KEGG: gym:GYMC10_5038 hypothetical protein; SPTR: B7C930 Putative uncharacterized protein (Fragment).
       0.661
Arch_0859
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: jde:Jden_1312 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: D0WMY6 Ribosomal RNA small subunit methyltransferase B; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.636
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.614
Arch_0747
COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: bcv:Bcav_1884 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WQL7 Binding protein; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
    
  0.555
Arch_0901
InterPro IPR001179; KEGG: bcv:Bcav_2236 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WMP5 Putative peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
    
  0.555
Arch_1507
COGs: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase 1; InterPro IPR001179; KEGG: bcv:Bcav_1060 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WQ01 Peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
    
  0.555
Arch_1789
KEGG: ckp:ckrop_1874 hypothetical protein; SPTR: C4LL85 Putative uncharacterized protein.
  
    0.499
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.