STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1792COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR018170:IPR001395:IPR020471; KEGG: mgi:Mflv_4697 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: A4TFA5 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family. (276 aa)    
Predicted Functional Partners:
Arch_1791
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: bcv:Bcav_3737 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: D0WLB7 Acyltransferase family protein; PFAM: Acyltransferase.
   
   0.787
Arch_1790
DSBA oxidoreductase; COGs: COG1651 Protein-disulfide isomerase; InterPro IPR012336:IPR017936:IPR001853:IPR012335; KEGG: cgt:cgR_0023 hypothetical protein; PFAM: DSBA oxidoreductase; SPTR: A4Q9U1 Putative uncharacterized protein; PFAM: DSBA-like thioredoxin domain.
  
    0.782
Arch_1793
Metal dependent phosphohydrolase; InterPro IPR003607:IPR006674:IPR006675; KEGG: tde:TDE1373 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q73MY3 HD domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
       0.781
Arch_1789
KEGG: ckp:ckrop_1874 hypothetical protein; SPTR: C4LL85 Putative uncharacterized protein.
       0.754
Arch_0910
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: xce:Xcel_1477 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: D1BS15 Aldo/keto reductase; PFAM: Aldo/keto reductase family.
 
 
 0.611
Arch_1788
KEGG: gym:GYMC10_5038 hypothetical protein; SPTR: B7C930 Putative uncharacterized protein (Fragment).
       0.522
Arch_1787
KEGG: fnu:FN1780 hypothetical protein; SPTR: D0WLC6 Putative uncharacterized protein.
  
    0.480
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
       0.455
Arch_0043
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585:IPR013785; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Q6AAL0 Transaldolase; PFAM: Transaldolase.
   
 
 0.416
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.