STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1806Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterProIPR003607:IPR002646:IPR006674:IPR014065:IPR 006675; KEGG: jde:Jden_2542 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: D0WL39 tRNA adenylyltransferase; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; manually curated; PFAM: HD domain; Poly A polymerase head [...] (497 aa)    
Predicted Functional Partners:
pnp
Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.746
Arch_1807
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
       0.683
Arch_1808
KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein.
       0.683
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.677
Arch_1809
Hypothetical protein; InterPro IPR011009; KEGG: xce:Xcel_3367 hypothetical protein; SPTR: D1BRV0 Putative uncharacterized protein.
       0.611
Arch_1803
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR001264:IPR001460; KEGG: bcv:Bcav_4182 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WL42 Penicillin-binding protein; manually curated; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
 
     0.604
Arch_1805
InterPro IPR016196:IPR011701; KEGG: bcv:Bcav_4203 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C1RM73 Major Facilitator Superfamily transporter; PFAM: Major Facilitator Superfamily.
       0.603
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
    0.601
whiB
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.595
Arch_0750
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
  
  
 0.586
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.