| node1 | node2 | node1 annotation | node2 annotation | score |
| Arch_0254 | Arch_1810 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.662 |
| Arch_0376 | Arch_1323 | COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: D0WRU8 Thioredoxin-related protein; PFAM: Thioredoxin. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.517 |
| Arch_0376 | Arch_1810 | COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: D0WRU8 Thioredoxin-related protein; PFAM: Thioredoxin. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.869 |
| Arch_0933 | Arch_1810 | Cysteine desulfurase, SufS subfamily; COGs: COG0520 Selenocysteine lyase; InterPro IPR015424:IPR015421:IPR010970:IPR000192; KEGG: xce:Xcel_1361 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: D0WMJ8 Cysteine desulfurase SufS; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.920 |
| Arch_1067 | Arch_1323 | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.682 |
| Arch_1067 | Arch_1810 | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.932 |
| Arch_1323 | Arch_0376 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: D0WRU8 Thioredoxin-related protein; PFAM: Thioredoxin. | 0.517 |
| Arch_1323 | Arch_1067 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. | 0.682 |
| Arch_1323 | Arch_1554 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2. | 0.936 |
| Arch_1323 | Arch_1810 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.890 |
| Arch_1554 | Arch_1323 | Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.936 |
| Arch_1554 | Arch_1810 | Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.800 |
| Arch_1807 | Arch_1808 | NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein. | 0.850 |
| Arch_1807 | Arch_1809 | NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | Hypothetical protein; InterPro IPR011009; KEGG: xce:Xcel_3367 hypothetical protein; SPTR: D1BRV0 Putative uncharacterized protein. | 0.729 |
| Arch_1807 | Arch_1810 | NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.654 |
| Arch_1807 | Arch_1811 | NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | Hypothetical protein; KEGG: csa:Csal_3245 ATP-dependent DNA helicase RecG. | 0.506 |
| Arch_1808 | Arch_1807 | KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein. | NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR015797:IPR020476:IPR000086; KEGG: bcv:Bcav_4208 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WL38 MutT/NUDIX family protein; manually curated; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. | 0.850 |
| Arch_1808 | Arch_1809 | KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein. | Hypothetical protein; InterPro IPR011009; KEGG: xce:Xcel_3367 hypothetical protein; SPTR: D1BRV0 Putative uncharacterized protein. | 0.917 |
| Arch_1808 | Arch_1810 | KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein. | COGs: COG0492 Thioredoxin reductase; InterPro IPR008255:IPR000103:IPR013027:IPR005982; KEGG: bfa:Bfae_31890 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: D0WL35 Thioredoxin-disulfide reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.658 |
| Arch_1808 | Arch_1811 | KEGG: bcv:Bcav_4209 hypothetical protein; SPTR: D0WL37 Putative uncharacterized protein. | Hypothetical protein; KEGG: csa:Csal_3245 ATP-dependent DNA helicase RecG. | 0.506 |