Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADI72936.1KEGG: mbu:Mbur_1734 peptidase S26B, signal peptidase; TIGRFAM: peptidase S26B, signal peptidase; PFAM: Peptidase S24/S26A/S26B, conserved region. (184 aa)    
Predicted Functional Partners:
ADI73649.1
PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein.
 
   
 0.927
ADI74508.1
Peptidase M50; KEGG: mbu:Mbur_0248 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.888
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
       0.802
atpE
H+transporting two-sector ATPase E subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.745
ADI74003.1
PFAM: Exosortase EpsH-related; KEGG: mbu:Mbur_2196 hypothetical protein.
  
   
 0.745
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
 
  
 0.736
ADI74124.1
PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: mbu:Mbur_1579 transmembrane oligosaccharyl transferase.
 
  
 0.714
ADI74773.1
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: mbu:Mbur_1362 replication factor A.
  
   
 0.698
ADI73998.1
PFAM: PRC-barrel domain protein; KEGG: mbu:Mbur_1465 PRC-barrel protein.
 
     0.683
ADI74772.1
KEGG: mbu:Mbur_1361 hypothetical protein.
  
     0.679
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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