Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73059.1PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; KEGG: mbu:Mbur_2115 phosphoglucosamine mutase; Belongs to the phosphohexose mutase family. (449 aa)    
Predicted Functional Partners:
ADI74235.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: mac:MA3140 mannose-1-phosphate guanylyltransferase (GDP).
 
 0.996
ADI73687.1
TIGRFAM: alpha-glucan phosphorylase; KEGG: mma:MM_3109 glycogen phosphorylase; PFAM: glycosyl transferase family 35.
 
 
 0.979
ADI74108.1
PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; manually curated; KEGG: mba:Mbar_A0229 mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
 
 
 0.959
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
 
 0.948
ADI74903.1
PFAM: glucose-6-phosphate isomerase; KEGG: mac:MA0821 hypothetical protein.
    
 0.921
fbp
Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.919
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.919
ADI74032.1
PFAM: Nucleotidyl transferase; KEGG: mem:Memar_0205 nucleotidyl transferase.
  
 0.913
pfkC
ADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
    
 0.909
ADI74978.1
PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase GAPDH domain protein; KEGG: mba:Mbar_A1040 myo-inositol-1-phosphate synthase.
    
 0.908
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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