Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73078.1AAA ATPase central domain protein; KEGG: mvu:Metvu_1206 AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase. (260 aa)    
Predicted Functional Partners:
ADI73077.1
KEGG: pfh:PFHG_05169 hypothetical protein.
       0.773
ADI73079.1
KEGG: pyo:PY00055 hypothetical protein.
       0.773
ADI73080.1
PFAM: SMC domain protein; KEGG: sto:ST2117 hypothetical protein.
 
 0.696
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
 0.681
ADI73323.1
SMART: AAA ATPase; TIGRFAM: 26S proteasome subunit P45 family; KEGG: mbu:Mbur_2301 proteasome-activating nucleotidase; PFAM: AAA ATPase central domain protein; Belongs to the AAA ATPase family.
 
 0.680
dnaK
Chaperone protein DnaK; Acts as a chaperone.
 
 0.638
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 
 0.556
ADI73119.1
KEGG: mbu:Mbur_2106 AAA ATPase; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
  
 
 
 0.555
ADI74019.1
KEGG: mbu:Mbur_0484 DEAD/DEAH box helicase-like protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; Protein of unknown function DUF1998; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: DEAD-like helicase; helicase domain protein; Tetratricopeptide repeat.
 
 0.553
ADI73622.1
PFAM: histone deacetylase superfamily; KEGG: mhu:Mhun_0929 histone deacetylase superfamily protein.
   
 0.551
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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