STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI73102.1PFAM: N-6 DNA methylase; KEGG: rci:RCIX973 type I restriction modification system, methyltransferase subunit. (482 aa)    
Predicted Functional Partners:
ADI73103.1
PFAM: restriction modification system DNA specificity domain; KEGG: rci:RCIX974 type I restriction modification system, specificity subunit (fragment).
 
 
 0.960
ADI73380.1
Protein of unknown function DUF450; KEGG: mba:Mbar_A1014 type I restriction-modification system restriction subunit; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase.
 
 
 0.947
ADI73379.1
PFAM: restriction modification system DNA specificity domain; KEGG: cyh:Cyan8802_3989 restriction modification system DNA specificity domain protein.
 
 
 0.934
ADI73093.1
KEGG: wsu:WS1649 DNA methylase-type I restriction-modification system.
 
 
 0.860
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.459
ADI73104.1
SMART: protein phosphatase 2C domain protein; KEGG: mvu:Metvu_1000 protein serine/threonine phosphatase.
       0.433
ADI73101.1
KEGG: tad:TRIADDRAFT_52674 hypothetical protein.
       0.424
ADI73094.1
PFAM: N-6 DNA methylase; protein of unknown function DUF450; KEGG: syp:SYNPCC7002_F0089 type I restriction modification system, N-6 DNA methylase.
  
     0.422
ADI74806.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: mbu:Mbur_1391 hypothetical protein.
  
  
 0.416
ADI73649.1
PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein.
     
 0.400
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.