STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (272 aa)    
Predicted Functional Partners:
ADI73129.1
PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: mba:Mbar_A3457 putative nucleotidyltransferase.
 
  
 0.989
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.934
ADI73037.1
TIGRFAM: precorrin-3B C17-methyltransferase; KEGG: mbu:Mbur_2356 precorrin-3 methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.923
ADI73131.1
Alpha-ribazole phosphatase CobZ; KEGG: mba:Mbar_A3455 hypothetical protein; TIGRFAM: alpha-ribazole phosphatase CobZ; PFAM: phosphatidylglycerophosphatase A.
 
  
  0.897
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.884
ADI73133.1
PFAM: aminotransferase class I and II; cysteine-rich small domain; KEGG: mba:Mbar_A3453 L-threonine O-3-phosphate decarboxylase.
 
   
 0.882
ADI73035.1
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mbu:Mbur_2359 cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.807
ADI73038.1
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mbu:Mbur_2355 precorrin-8X methylmutase.
 
  
 0.797
ADI73036.1
TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: mba:Mbar_A0627 cobalt-factor II C20-methyltransferase / precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.751
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
  
 0.747
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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