| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI73190.1 | ADI73191.1 | Metev_0262 | Metev_0263 | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 0.940 |
| ADI73190.1 | cofC | Metev_0262 | Metev_0264 | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.492 |
| ADI73190.1 | cofH | Metev_0262 | Metev_0265 | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.457 |
| ADI73191.1 | ADI73190.1 | Metev_0263 | Metev_0262 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.940 |
| ADI73191.1 | ADI73940.1 | Metev_0263 | Metev_1054 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | KEGG: mma:MM_0138 hypothetical protein. | 0.434 |
| ADI73191.1 | ADI74023.1 | Metev_0263 | Metev_1141 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | PFAM: phosphoadenosine phosphosulfate reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1327 hypothetical protein. | 0.430 |
| ADI73191.1 | ADI74768.1 | Metev_0263 | Metev_1938 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | PFAM: conserved hypothetical protein; KEGG: mma:MM_0288 ArsR family transcriptional regulator. | 0.555 |
| ADI73191.1 | ADI74837.1 | Metev_0263 | Metev_2008 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mac:MA0067 hypothetical protein. | 0.616 |
| ADI73191.1 | cofC | Metev_0263 | Metev_0264 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.467 |
| ADI73191.1 | cofH | Metev_0263 | Metev_0265 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.427 |
| ADI73191.1 | trmY | Metev_0263 | Metev_1628 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. | 0.410 |
| ADI73940.1 | ADI73191.1 | Metev_1054 | Metev_0263 | KEGG: mma:MM_0138 hypothetical protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 0.434 |
| ADI73940.1 | ADI74768.1 | Metev_1054 | Metev_1938 | KEGG: mma:MM_0138 hypothetical protein. | PFAM: conserved hypothetical protein; KEGG: mma:MM_0288 ArsR family transcriptional regulator. | 0.746 |
| ADI73940.1 | ADI74837.1 | Metev_1054 | Metev_2008 | KEGG: mma:MM_0138 hypothetical protein. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mac:MA0067 hypothetical protein. | 0.470 |
| ADI74023.1 | ADI73191.1 | Metev_1141 | Metev_0263 | PFAM: phosphoadenosine phosphosulfate reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1327 hypothetical protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 0.430 |
| ADI74023.1 | ADI74837.1 | Metev_1141 | Metev_2008 | PFAM: phosphoadenosine phosphosulfate reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1327 hypothetical protein. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mac:MA0067 hypothetical protein. | 0.442 |
| ADI74023.1 | trmY | Metev_1141 | Metev_1628 | PFAM: phosphoadenosine phosphosulfate reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1327 hypothetical protein. | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. | 0.461 |
| ADI74768.1 | ADI73191.1 | Metev_1938 | Metev_0263 | PFAM: conserved hypothetical protein; KEGG: mma:MM_0288 ArsR family transcriptional regulator. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1307 4Fe-4S ferredoxin, iron-sulfur binding. | 0.555 |
| ADI74768.1 | ADI73940.1 | Metev_1938 | Metev_1054 | PFAM: conserved hypothetical protein; KEGG: mma:MM_0288 ArsR family transcriptional regulator. | KEGG: mma:MM_0138 hypothetical protein. | 0.746 |
| ADI74768.1 | ADI74837.1 | Metev_1938 | Metev_2008 | PFAM: conserved hypothetical protein; KEGG: mma:MM_0288 ArsR family transcriptional regulator. | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mac:MA0067 hypothetical protein. | 0.669 |