Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73412.1KEGG: mac:MA4087 molybdenum cofactor biosynthesis protein MoeA2; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV. (399 aa)    
Predicted Functional Partners:
ADI73409.1
KEGG: mba:Mbar_A1367 molybdenum cofactor biosynthesis protein B; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain.
 
 0.990
ADI74715.1
KEGG: mac:MA4350 molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV.
 
 
0.981
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
 0.974
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.955
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.928
ADI73413.1
MoaD family protein; KEGG: mma:MM_0831 molybdopterin converting factor small subunit; TIGRFAM: MoaD family protein; PFAM: thiamineS protein.
  
  
 0.879
ADI74499.1
KEGG: mbu:Mbur_0381 molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin-guanine dinucleotide biosynthesis MobB region.
 
  
 0.814
ADI74603.1
Putative transcriptional regulator, ModE family; PFAM: TOBE domain protein; regulatory protein LysR; KEGG: mac:MA0283 molybdenum-binding protein.
 
   
 0.724
ADI74604.1
KEGG: mac:MA0282 sulfate/molybdate ABC transporter, ATP-binding protein; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase.
 
  
 0.657
ADI73877.1
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mac:MA0255 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF.
 
  
 0.607
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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